| Reaction Details |
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 | Report a problem with these data |
| Target | N-arachidonyl glycine receptor |
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| Ligand | BDBM50221681 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2075768 (CHEMBL4731302) |
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| IC50 | >10000±n/a nM |
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| Citation |  Schoeder, CT; Mahardhika, AB; Drabczy?ska, A; Kie?-Kononowicz, K; Müller, CE Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18. ACS Med Chem Lett11:2024-2031 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-arachidonyl glycine receptor |
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| Name: | N-arachidonyl glycine receptor |
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| Synonyms: | G-protein coupled receptor 18 | GPCRW | GPR18 | GPR18_HUMAN | NAGly receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38150.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107601 |
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| Residue: | 331 |
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| Sequence: | MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY
MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY
MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY
LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ
VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV
MLYRNYLRSMRRKSFRSGSLRSLSNINSEML
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| BDBM50221681 |
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| n/a |
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| Name | BDBM50221681 |
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| Synonyms: | 9-(4-chlorophenethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione | CHEMBL239230 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20ClN5O2 |
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| Mol. Mass. | 373.837 |
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| SMILES | Cn1c2nc3N(CCc4ccc(Cl)cc4)CCCn3c2c(=O)n(C)c1=O |
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| Structure | 
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