| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50124775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105836 (CHEMBL716495) |
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| IC50 | 70±n/a nM |
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| Citation |  Danho, W; Swistok, J; Cheung, AW; Kurylko, G; Franco, L; Chu, XJ; Chen, L; Yagaloff, K Structure-activity relationship of linear peptide Bu-His6-DPhe7-Arg8-Trp9-Gly10-NH2 at the human melanocortin-1 and -4 receptors: DPhe7 and Trp9 substitution. Bioorg Med Chem Lett13:649-52 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 34717.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q01726 |
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| Residue: | 317 |
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| Sequence: | MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV
ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI
DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI
AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA
VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF
HSQELRRTLKEVLTCSW
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| BDBM50124775 |
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| n/a |
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| Name | BDBM50124775 |
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| Synonyms: | (S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(4-methoxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide | CHEMBL345234 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H52N12O7 |
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| Mol. Mass. | 800.9064 |
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| SMILES | CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O |
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| Structure | 
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