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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Integrase | ||
| Ligand | BDBM50124964 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_90713 (CHEMBL702112) | ||
| IC50 | 8000±n/a nM | ||
| Citation |  Singh, SB; Zink, DL; Bills, GF; Teran, A; Silverman, KC; Lingham, RB; Felock, P; Hazuda, DJ Four novel bis-(naphtho-gamma-pyrones) isolated from Fusarium species as inhibitors of HIV-1 integrase. Bioorg Med Chem Lett13:713-7 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Integrase | |||
| Name: | Integrase | ||
| Synonyms: | Human immunodeficiency virus type 1 integrase | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 32231.48 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_90865 | ||
| Residue: | 288 | ||
| Sequence: |
| ||
| BDBM50124964 | |||
| n/a | |||
| Name | BDBM50124964 | ||
| Synonyms: | 6,8'-Dihydroxy-5,8,5',6'-tetramethoxy-2,3,2',3'-tetramethyl-2,3,2',3'-tetrahydro-[9,9']bi[benzo[g]chromenyl]-4,4'-dione | CHEMBL349440 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H34O10 | ||
| Mol. Mass. | 602.6278 | ||
| SMILES | COc1cc(O)c2c(OC)c3C(=O)C(C)C(C)Oc3cc2c1-c1c(O)cc(OC)c2c(OC)c3C(=O)C(C)C(C)Oc3cc12 |(-4.08,-12.58,;-2.99,-11.49,;-1.66,-12.26,;-1.65,-13.8,;-.32,-14.57,;-.3,-16.08,;1.01,-13.77,;2.34,-14.54,;2.36,-16.06,;1.26,-17.16,;3.66,-13.75,;4.99,-14.52,;4.98,-16.06,;6.31,-13.75,;7.66,-14.5,;6.31,-12.21,;7.63,-11.42,;4.97,-11.44,;3.65,-12.23,;2.32,-11.46,;1.01,-12.23,;-.32,-11.49,;-.33,-9.95,;-1.66,-9.18,;-3,-9.95,;-1.66,-7.64,;-.33,-6.87,;-.33,-5.33,;-1.66,-4.56,;1.01,-7.64,;2.33,-6.84,;2.33,-5.3,;1.24,-4.21,;3.67,-7.61,;5,-6.84,;4.99,-5.3,;6.33,-7.59,;7.66,-6.8,;6.35,-9.15,;7.7,-9.9,;5.02,-9.92,;3.67,-9.15,;2.34,-9.95,;1.01,-9.18,)| | ||
| Structure | 
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