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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Integrase | ||
| Ligand | BDBM50124965 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_90713 (CHEMBL702112) | ||
| IC50 | 80000±n/a nM | ||
| Citation |  Singh, SB; Zink, DL; Bills, GF; Teran, A; Silverman, KC; Lingham, RB; Felock, P; Hazuda, DJ Four novel bis-(naphtho-gamma-pyrones) isolated from Fusarium species as inhibitors of HIV-1 integrase. Bioorg Med Chem Lett13:713-7 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Integrase | |||
| Name: | Integrase | ||
| Synonyms: | Human immunodeficiency virus type 1 integrase | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 32231.48 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_90865 | ||
| Residue: | 288 | ||
| Sequence: |
| ||
| BDBM50124965 | |||
| n/a | |||
| Name | BDBM50124965 | ||
| Synonyms: | 5,6-Dihydroxy-8,5',6',8'-tetramethoxy-2,3,2',3'-tetramethyl-2,3,2',3'-tetrahydro-[9,9']bi[benzo[g]chromenyl]-4,4'-dione | CHEMBL350391 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H34O10 | ||
| Mol. Mass. | 602.6278 | ||
| SMILES | COc1cc(O)c2c(O)c3C(=O)C(C)C(C)Oc3cc2c1-c1c(OC)cc(OC)c2c(OC)c3C(=O)C(C)C(C)Oc3cc12 |(-4.1,-12.46,;-3.01,-11.38,;-1.67,-12.13,;-1.66,-13.68,;-.33,-14.45,;-.32,-15.98,;1,-13.67,;2.34,-14.42,;2.34,-15.96,;3.65,-13.65,;4.98,-14.42,;4.98,-15.96,;6.31,-13.63,;7.66,-14.39,;6.31,-12.09,;7.62,-11.31,;4.96,-11.33,;3.65,-12.11,;2.31,-11.36,;1,-12.13,;-.33,-11.36,;-.34,-9.84,;-1.67,-9.07,;-3.01,-9.82,;-4.51,-9.42,;-1.67,-7.51,;-.34,-6.74,;-.34,-5.21,;-1.67,-4.44,;1,-7.51,;2.32,-6.73,;2.32,-5.19,;1.22,-4.09,;3.67,-7.48,;5,-6.71,;4.98,-5.17,;6.33,-7.48,;7.66,-6.68,;6.36,-9.03,;7.69,-9.79,;5.01,-9.81,;3.67,-9.04,;2.34,-9.82,;1,-9.05,)| | ||
| Structure | 
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