| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
|---|
| Ligand | BDBM50126021 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_153535 (CHEMBL765404) |
|---|
| IC50 | 7400±n/a nM |
|---|
| Citation |  Santini, C; Berger, GD; Han, W; Mosley, R; MacNaul, K; Berger, J; Doebber, T; Wu, M; Moller, DE; Tolman, RL; Sahoo, SP Phenylacetic acid derivatives as hPPAR agonists. Bioorg Med Chem Lett13:1277-80 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor alpha |
|---|
| Name: | Peroxisome proliferator-activated receptor alpha |
|---|
| Synonyms: | NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52222.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q07869 |
|---|
| Residue: | 468 |
|---|
| Sequence: | MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSC
PGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFV
IHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDI
FLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
|
|
|
|---|
| BDBM50126021 |
|---|
| n/a |
|---|
| Name | BDBM50126021 |
|---|
| Synonyms: | CHEMBL23881 | {4-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-propylsulfanyl]-3-chloro-phenyl}-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H25ClO5S |
|---|
| Mol. Mass. | 436.949 |
|---|
| SMILES | CCCc1c(O)c(ccc1OCCCSc1ccc(CC(O)=O)cc1Cl)C(C)=O |
|---|
| Structure | 
|
|---|
Search and Browse
