| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50002133 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_38164 |
|---|
| EC50 | 290±n/a nM |
|---|
| Citation |  Harada, H; Hirokawa, Y; Suzuki, K; Hiyama, Y; Oue, M; Kawashima, H; Yoshida, N; Furutani, Y; Kato, S Novel and potent human and rat beta3-adrenergic receptor agonists containing substituted 3-indolylalkylamines. Bioorg Med Chem Lett13:1301-5 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46461.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07550 |
|---|
| Residue: | 413 |
|---|
| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50002133 |
|---|
| n/a |
|---|
| Name | BDBM50002133 |
|---|
| Synonyms: | (+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propyl)phenoxy)acetic acid | (4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (4-{2-[(R)-2-((R)-3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (BRL 37,344)(4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | (R*, R*) (4-{2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxy)-acetic acid | 2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)propyl)phenoxy)acetic acid | BRL-37344 | CHEMBL284782 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H22ClNO4 |
|---|
| Mol. Mass. | 363.835 |
|---|
| SMILES | C[C@H](Cc1ccc(OCC(O)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
