| Reaction Details |
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 | Report a problem with these data |
| Target | Ecdysone receptor |
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| Ligand | BDBM50128299 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_65456 |
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| EC50 | 3680±n/a nM |
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| Citation |  Tice, CM; Hormann, RE; Thompson, CS; Friz, JL; Cavanaugh, CK; Saggers, JA Optimization of alpha-acylaminoketone ecdysone agonists for control of gene expression. Bioorg Med Chem Lett13:1883-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Ecdysone receptor |
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| Name: | Ecdysone receptor |
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| Synonyms: | 20-hydroxy-ecdysone receptor | 20E receptor | ECR_BOMMO | EcR | EcRH | Ecdysteroid receptor | NR1H1 | Nuclear receptor subfamily 1 group H member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68199.29 |
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| Organism: | Bombyx mori |
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| Description: | ChEMBL_65456 |
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| Residue: | 606 |
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| Sequence: | MRVENVDNVSFALNGRADEWCMSVETRLDSLVREKSEVKAYVGGCPSVITDAGAYDALFD
MRRRWSNNGGFPLRMLEESSSEVTSSSALGLPPAMVMSPESLASPEYRALELWSYDDGIT
YNTAQSLLGACNMQQQQLQPQQPHPAPPTLPTMPLPMPPTTPKSENESMSSGREELSPAS
SINGCSADADARRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAV
YICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVIQEPSKNKDRQRQKKDKGILLPV
STTTVEDHMPPIMQCDPPPPEAARIHEVVPRYLSEKLMEQNRQKNIPPLSANQKSLIARL
VWYQEGYEQPSDEDLKRVTQTWQSDEEDEESDLPFRQITEMTILTVQLIVEFAKGLPGFS
KISQSDQITLLKASSSEVMMLRVARRYDAASDSVLFANNKAYTRDNYRQGGMAYVIEDLL
HFCRCMFAMGMDNVHFALLTAIVIFSDRPGLEQPSLVEEIQRYYLNTLRIYIINQNSASS
RCAVIYGRILSVLTELRTLGTQNSNMCISLKLKNRKLPPFLEEIWDVAEVATTHPTVLPP
TNPVVL
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| BDBM50128299 |
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| n/a |
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| Name | BDBM50128299 |
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| Synonyms: | 4-Methyl-benzo[1,3]dioxole-5-carboxylic acid [1-(3,5-dimethyl-benzoyl)-cyclohexyl]-amide | CHEMBL294845 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27NO4 |
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| Mol. Mass. | 393.4755 |
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| SMILES | Cc1cc(C)cc(c1)C(=O)C1(CCCCC1)NC(=O)c1ccc2OCOc2c1C |
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| Structure | 
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