| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
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| Ligand | BDBM50128694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157789 (CHEMBL767848) |
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| IC50 | 15±n/a nM |
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| Citation |  Mitsumori, S; Tsuri, T; Honma, T; Hiramatsu, Y; Okada, T; Hashizume, H; Inagaki, M; Arimura, A; Yasui, K; Asanuma, F; Kishino, J; Ohtani, M Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 1. Bicyclo[2.2.1]heptane derivatives. J Med Chem46:2436-45 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor |
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| Name: | Prostaglandin D2 receptor |
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| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40288.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13258 |
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| Residue: | 359 |
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| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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| BDBM50128694 |
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| n/a |
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| Name | BDBM50128694 |
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| Synonyms: | (+) 7-{3-[2-(4-Methoxy-phenyl)-1H-indole-6-sulfonylamino]-bicyclo[2.2.1]hept-2-yl}-hept-5-enoic acid | CHEMBL311199 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H34N2O5S |
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| Mol. Mass. | 522.656 |
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| SMILES | COc1ccc(cc1)-c1cc2ccc(cc2[nH]1)S(=O)(=O)N[C@@H]1[C@@H]2CC[C@@H](C2)[C@H]1C\C=C/CCCC(O)=O |
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| Structure | 
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