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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Calcium-activated potassium channel subunit alpha-1 | ||
| Ligand | BDBM50128979 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_39096 | ||
| EC50 | 4430.0±n/a nM | ||
| Citation |  Turner, SC; Carroll, WA; White, TK; Gopalakrishnan, M; Coghlan, MJ; Shieh, CC; Zhang, XF; Parihar, AS; Buckner, SA; Milicic, I; Sullivan, JP The discovery of a new class of large-conductance Ca2+-activated K+ channel opener targeted for overactive bladder: synthesis and structure-activity relationships of 2-amino-4-azaindoles. Bioorg Med Chem Lett13:2003-7 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Calcium-activated potassium channel subunit alpha-1 | |||
| Name: | Calcium-activated potassium channel subunit alpha-1 | ||
| Synonyms: | Calcium-activated potassium channel alpha/beta 1 | KCMA1_HUMAN | KCNMA | KCNMA1 | Large conductance calcium-activated potassium channel subfamily M alpha member 1 isoform b | SLO | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 137567.62 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_938830 | ||
| Residue: | 1236 | ||
| Sequence: |
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| BDBM50128979 | |||
| n/a | |||
| Name | BDBM50128979 | ||
| Synonyms: | 2-(3-Aza-bicyclo[3.2.2]non-3-yl)-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile | CHEMBL303805 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H18N4 | ||
| Mol. Mass. | 266.3409 | ||
| SMILES | N#Cc1c([nH]c2cccnc12)N1CC2CCC(CC2)C1 |(7.82,.09,;7.33,-1.38,;6.86,-2.85,;7.77,-4.11,;6.86,-5.34,;5.4,-4.88,;4.07,-5.65,;2.73,-4.88,;2.73,-3.34,;4.07,-2.57,;5.4,-3.34,;9.31,-4.18,;10.13,-2.89,;11.67,-2.71,;12.75,-3.81,;12.6,-5.34,;11.29,-6.16,;10.48,-4.88,;10.53,-3.72,;9.82,-5.65,)| | ||
| Structure | 
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