| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50233089 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2094398 (CHEMBL4775661) |
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| Ki | 6.0±n/a nM |
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| Citation |  Majellaro, M; Jespers, W; Crespo, A; Núñez, MJ; Novio, S; Azuaje, J; Prieto-Díaz, R; Gioé, C; Alispahic, B; Brea, J; Loza, MI; Freire-Garabal, M; Garcia-Santiago, C; Rodríguez-García, C; García-Mera, X; Caamaño, O; Fernandez-Masaguer, C; Sardina, JF; Stefanachi, A; El Maatougui, A; Mallo-Abreu, A; Åqvist, J; Gutiérrez-de-Terán, H; Sotelo, E 3,4-Dihydropyrimidin-2(1 J Med Chem64:458-480 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50233089 |
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| n/a |
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| Name | BDBM50233089 |
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| Synonyms: | 8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-1-propyl-1H-purine-2,6(3H,7H)-dione | CHEMBL404168 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17F3N6O2 |
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| Mol. Mass. | 418.3725 |
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| SMILES | CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1cnn(Cc2cccc(c2)C(F)(F)F)c1 |
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| Structure | 
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