| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase, mitochondrial |
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| Ligand | BDBM50131289 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154178 |
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| IC50 | 30±n/a nM |
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| Citation |  Davies, SJ; Ayscough, AP; Beckett, RP; Bragg, RA; Clements, JM; Doel, S; Grew, C; Launchbury, SB; Perkins, GM; Pratt, LM; Smith, HK; Spavold, ZM; Thomas, SW; Todd, RS; Whittaker, M Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain. Bioorg Med Chem Lett13:2709-13 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase, mitochondrial |
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| Name: | Peptide deformylase, mitochondrial |
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| Synonyms: | DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27023.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_154318 |
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| Residue: | 243 |
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| Sequence: | MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPP
EPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPR
QVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLA
CVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMK
VND
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|
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| BDBM50131289 |
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| n/a |
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| Name | BDBM50131289 |
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| Synonyms: | (R)-2-[(Formyl-hydroxy-amino)-methyl]-pent-4-enoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide | CHEMBL93648 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H27N3O4 |
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| Mol. Mass. | 313.3926 |
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| SMILES | CN(C)C(=O)[C@@H](NC(=O)[C@H](CC=C)CN(O)C=O)C(C)(C)C |
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| Structure | 
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