| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50099814 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60196 (CHEMBL674339) |
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| Ki | 7400±n/a nM |
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| Citation |  Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hübner, H; Gmeiner, P Stereocontrolled dopamine receptor binding and subtype selectivity of clebopride analogues synthesized from aspartic acid. Bioorg Med Chem Lett13:3293-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | D(1A) dopamine receptor | D1AR | DOPAMINE D1 | DRD1 | DRD1_BOVIN | Dopamine receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49330.65 |
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| Organism: | BOVINE |
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| Description: | DOPAMINE D1 DRD1 BOVINE::Q95136 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLG
KTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKN
CQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGS
GETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50099814 |
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| n/a |
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| Name | BDBM50099814 |
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| Synonyms: | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide | CHEMBL298875 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23BrN2O2 |
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| Mol. Mass. | 439.345 |
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| SMILES | COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 |
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| Structure | 
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