Compile Data Set for Download or QSAR

Found 1679 hits with Last Name = 'lehmann' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50116766 ((-)-Pramipexole | (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 |r| Show InChI InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D3 expressed in CHO cells				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranes				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM84637 (CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...) Show SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r| Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cells				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human cloned dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranes				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132699 (4-Ethynyl-1-methoxy-naphthalene-2-carboxylic acid ...) Show SMILES COc1c(cc(C#C)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C25H24N2O2/c1-3-19-15-23(24(29-2)22-12-8-7-11-21(19)22)25(28)26-20-13-14-27(17-20)16-18-9-5-4-6-10-18/h1,4-12,15,20H,13-14,16-17H2,2H3,(H,26,28)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132699 (4-Ethynyl-1-methoxy-naphthalene-2-carboxylic acid ...) Show SMILES COc1c(cc(C#C)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C25H24N2O2/c1-3-19-15-23(24(29-2)22-12-8-7-11-21(19)22)25(28)26-20-13-14-27(17-20)16-18-9-5-4-6-10-18/h1,4-12,15,20H,13-14,16-17H2,2H3,(H,26,28)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132696 (CHEMBL326454 | N-((3R,4R)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132693 (4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132689 (4-Iodo-1-methoxy-naphthalene-2-carboxylic acid ((R...) Show SMILES COc1c(cc(I)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H23IN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132689 (4-Iodo-1-methoxy-naphthalene-2-carboxylic acid ((R...) Show SMILES COc1c(cc(I)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H23IN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50107746 (CHEMBL3600828) Show SMILES Clc1ccc(cc1)-c1ccc(nc1)C#Cc1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C25H23ClN2O/c26-23-9-6-21(7-10-23)22-8-12-24(27-19-22)11-3-20-4-13-25(14-5-20)29-18-17-28-15-1-2-16-28/h4-10,12-14,19H,1-2,15-18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Antagonist activity against rat MCHR1				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132703 (CHEMBL111749 | N-((3R,4S)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132703 (CHEMBL111749 | N-((3R,4S)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132695 (CHEMBL109912 | N-((3S,4S)-1-Benzyl-3-methyl-piperi...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C22H28ClN3O2/c1-15-13-26(14-16-7-5-4-6-8-16)10-9-19(15)25-22(27)17-11-18(23)20(24-2)12-21(17)28-3/h4-8,11-12,15,19,24H,9-10,13-14H2,1-3H3,(H,25,27)/t15-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132695 (CHEMBL109912 | N-((3S,4S)-1-Benzyl-3-methyl-piperi...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C22H28ClN3O2/c1-15-13-26(14-16-7-5-4-6-8-16)10-9-19(15)25-22(27)17-11-18(23)20(24-2)12-21(17)28-3/h4-8,11-12,15,19,24H,9-10,13-14H2,1-3H3,(H,25,27)/t15-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50099814 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H23BrN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.				Bioorg Med Chem Lett 11: 2863-6 (2001) BindingDB Entry DOI: 10.7270/Q2D799Q9
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50099814 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H23BrN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50105731 ((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...) Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D3 expressed in CHO cells				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50105731 ((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...) Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.				Bioorg Med Chem Lett 11: 2863-6 (2001) BindingDB Entry DOI: 10.7270/Q2D799Q9
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50105731 ((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...) Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O Show InChI InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-spiperone from bovine cloned Dopamine receptor D2 stably expressed in CHO cells.				Bioorg Med Chem Lett 11: 2863-6 (2001) BindingDB Entry DOI: 10.7270/Q2D799Q9
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50164427 ((S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-...) Show SMILES CCCN(CCC)[C@H]1CCn2c(C1)ccc2C#N Show InChI InChI=1S/C15H23N3/c1-3-8-17(9-4-2)13-7-10-18-14(11-13)5-6-15(18)12-16/h5-6,13H,3-4,7-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D3 expressed in CHO cells				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranes				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-Pramipexole from high affinity binding sites of bovine cloned D2 receptors stably expressed in CHO cells.				Bioorg Med Chem Lett 11: 2863-6 (2001) BindingDB Entry DOI: 10.7270/Q2D799Q9
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50054067 ((2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-spiperone from human cloned Dopamine receptor D3 stably expressed in CHO cells.				Bioorg Med Chem Lett 11: 2863-6 (2001) BindingDB Entry DOI: 10.7270/Q2D799Q9
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50116766 ((-)-Pramipexole | (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 |r| Show InChI InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cells				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132701 (CHEMBL112395 | N-(1-Benzyl-piperidin-4-yl)-5-chlor...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H26ClN3O2/c1-23-19-13-20(27-2)17(12-18(19)22)21(26)24-16-8-10-25(11-9-16)14-15-6-4-3-5-7-15/h3-7,12-13,16,23H,8-11,14H2,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132703 (CHEMBL111749 | N-((3R,4S)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132703 (CHEMBL111749 | N-((3R,4S)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132693 (4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM142122 (US8933079, 149 | US8933079, 150 | US8933079, 9.1) Show SMILES COc1ccc(COc2cnn(CC(=O)c3ccc(CN(C)C)cc3C)c(=O)c2)nc1 Show InChI InChI=1S/C23H26N4O4/c1-16-9-17(13-26(2)3)5-8-21(16)22(28)14-27-23(29)10-20(12-25-27)31-15-18-6-7-19(30-4)11-24-18/h5-12H,13-15H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Binding affinity to human MCH-R1 expressed in CHO/Galpha16 cells				Bioorg Med Chem Lett 25: 3275-80 (2015) Article DOI: 10.1016/j.bmcl.2015.05.065 BindingDB Entry DOI: 10.7270/Q2T43VV4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132703 (CHEMBL111749 | N-((3R,4S)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from human recombinant dopamine receptor D2L expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132701 (CHEMBL112395 | N-(1-Benzyl-piperidin-4-yl)-5-chlor...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H26ClN3O2/c1-23-19-13-20(27-2)17(12-18(19)22)21(26)24-16-8-10-25(11-9-16)14-15-6-4-3-5-7-15/h3-7,12-13,16,23H,8-11,14H2,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132703 (CHEMBL111749 | N-((3R,4S)-1-Benzyl-4-methyl-pyrrol...) Show SMILES CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-11-25(12-15-7-5-4-6-8-15)13-19(14)24-21(26)16-9-17(22)18(23-2)10-20(16)27-3/h4-10,14,19,23H,11-13H2,1-3H3,(H,24,26)/t14-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranes				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132691 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C24H25BrN2O2/c1-16-13-27(14-17-8-4-3-5-9-17)15-22(16)26-24(28)20-12-21(25)18-10-6-7-11-19(18)23(20)29-2/h3-12,16,22H,13-15H2,1-2H3,(H,26,28)/t16-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.2-0.45 nM)] from human recombinant dopamine receptor D2S expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50132691 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C24H25BrN2O2/c1-16-13-27(14-17-8-4-3-5-9-17)15-22(16)26-24(28)20-12-21(25)18-10-6-7-11-19(18)23(20)29-2/h3-12,16,22H,13-15H2,1-2H3,(H,26,28)/t16-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone [0.5 nM (Kd=0.1-0.45 nM)] from human recombinant dopamine receptor D4 expressed in CHO cells				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132693 (4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23,390 [0.3 nM (Kd=0.35 nM)] from dopamine receptor D1 in bovine striatal membranes				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132700 (4-Amino-N-((3S,4S)-1-benzyl-3-methyl-piperidin-4-y...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C[C@@H]1C Show InChI InChI=1S/C21H26ClN3O2/c1-14-12-25(13-15-6-4-3-5-7-15)9-8-19(14)24-21(26)16-10-17(22)18(23)11-20(16)27-2/h3-7,10-11,14,19H,8-9,12-13,23H2,1-2H3,(H,24,26)/t14-,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone [0.5 nM (Kd=0.1 nM)] from recombinant human dopamine receptor D3 expressed in CHO cells at 0.5 nM concentration				Bioorg Med Chem Lett 13: 3293-6 (2003) BindingDB Entry DOI: 10.7270/Q2639P5F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50116766 ((-)-Pramipexole | (6S)-N(6)-propyl-4,5,6,7-tetrahy...) Show SMILES CCCN[C@H]1CCc2nc(N)sc2C1 |r| Show InChI InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D2L expressed in CHO cells				J Med Chem 48: 2493-508 (2005) Article DOI: 10.1021/jm049269+ BindingDB Entry DOI: 10.7270/Q2TT4QGT
					More data for this Ligand-Target Pair

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