| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50568752 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2106796 (CHEMBL4815471) |
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| Ki | 31±n/a nM |
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| Citation |  Biselli, S; Bresinsky, M; Tropmann, K; Forster, L; Honisch, C; Buschauer, A; Bernhardt, G; Pockes, S Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H Eur J Med Chem214:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40115.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 359 |
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| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
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| BDBM50568752 |
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| n/a |
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| Name | BDBM50568752 |
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| Synonyms: | CHEMBL4869194 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N6OS |
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| Mol. Mass. | 374.504 |
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| SMILES | CC(NC(=O)\N=C(/N)NCCCc1sc(N)nc1C)c1ccc(C)cc1 |
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| Structure | 
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