| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50036733 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2106946 (CHEMBL4815621) |
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| Ki | 6.3±n/a nM |
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| Citation |  Ofori, E; Onyameh, EK; Gonela, UM; Voshavar, C; Bricker, B; Swanson, TL; Eshleman, AJ; Schmachtenberg, JL; Bloom, SH; Janowsky, AJ; Ablordeppey, SY New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263. Eur J Med Chem214:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50036733 |
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| n/a |
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| Name | BDBM50036733 |
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| Synonyms: | 1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one(Azaperone) | Azaperone | CHEMBL340211 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22FN3O |
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| Mol. Mass. | 327.3959 |
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| SMILES | Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ccccn1 |
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| Structure | 
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