| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
|---|
| Ligand | BDBM50036733 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2106947 (CHEMBL4815622) |
|---|
| Ki | 7.6±n/a nM |
|---|
| Citation |  Ofori, E; Onyameh, EK; Gonela, UM; Voshavar, C; Bricker, B; Swanson, TL; Eshleman, AJ; Schmachtenberg, JL; Bloom, SH; Janowsky, AJ; Ablordeppey, SY New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263. Eur J Med Chem214:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1A |
|---|
| Name: | 5-hydroxytryptamine receptor 1A |
|---|
| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46122.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 422 |
|---|
| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
|
|
|
|---|
| BDBM50036733 |
|---|
| n/a |
|---|
| Name | BDBM50036733 |
|---|
| Synonyms: | 1-(4-Fluoro-phenyl)-4-(4-pyridin-2-yl-piperazin-1-yl)-butan-1-one(Azaperone) | Azaperone | CHEMBL340211 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H22FN3O |
|---|
| Mol. Mass. | 327.3959 |
|---|
| SMILES | Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ccccn1 |
|---|
| Structure | 
|
|---|
Search and Browse
