| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK3 |
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| Ligand | BDBM50568997 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2107269 (CHEMBL4815944) |
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| IC50 | >10000±n/a nM |
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| Citation |  Zhang, Y; Xia, A; Zhang, S; Lin, G; Liu, J; Chen, P; Mu, B; Jiao, Y; Xu, W; Chen, M; Li, L Discovery of 3,6-disubstutited-imidazo[1,2-a]pyridine derivatives as a new class of CLK1 inhibitors. Bioorg Med Chem Lett41:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK3 |
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| Name: | Dual specificity protein kinase CLK3 |
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| Synonyms: | CDC2-like kinase 3 (CLK3) | CLK3 | CLK3_HUMAN | Dual specificity protein kinase CLK3 |
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| Type: | Protein |
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| Mol. Mass.: | 73570.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 638 |
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| Sequence: | MPVLSARRRELADHAGSGRRSGPSPTARSGPHLSALRAQPARAAHLSGRGTYVRRDTAGG
GPGQARPLGPPGTSLLGRGARRSGEGWCPGAFESGARAARPPSRVEPRLATAASREGAGL
PRAEVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEG
RLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHR
RRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWL
QERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKD
KENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALR
FLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHT
TIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGP
IPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRM
LEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
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| BDBM50568997 |
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| n/a |
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| Name | BDBM50568997 |
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| Synonyms: | CHEMBL4853178 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H20N4O2 |
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| Mol. Mass. | 408.4519 |
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| SMILES | COc1ccc(CNC(=O)c2cnc3ccc(cn23)-c2ccc3ncccc3c2)cc1 |
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| Structure | 
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