| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Toll-like receptor 2 |
|---|
| Ligand | BDBM50570372 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2112057 (CHEMBL4820907) |
|---|
| IC50 | >30000±n/a nM |
|---|
| Citation |  Natala, SR; Habas, A; Stocking, EM; Orry, A; Price, DL; Gill, MB; Bonhaus, DW; Abagyan, R; Wrasidlo, W Structure based design and synthesis of novel Toll-like Receptor 2 (TLR 2) lipid antagonists. Bioorg Med Chem Lett40:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Toll-like receptor 2 |
|---|
| Name: | Toll-like receptor 2 |
|---|
| Synonyms: | TIL4 | TLR2 | TLR2_HUMAN | Toll-like receptor 2 | Toll-like receptor 2 (TLR2) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 89837.58 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O60603 |
|---|
| Residue: | 784 |
|---|
| Sequence: | MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLS
NNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWF
KPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELE
IDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFS
ELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDN
DRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLK
SLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDI
SKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLK
ELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCE
FLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFL
LILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMV
QELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFS
HFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRA
AIKS
|
|
|
|---|
| BDBM50570372 |
|---|
| n/a |
|---|
| Name | BDBM50570372 |
|---|
| Synonyms: | CHEMBL4865889 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C44H84ClN3O3 |
|---|
| Mol. Mass. | 738.609 |
|---|
| SMILES | Cl.CCCCCCCCCCCCCCOCC(CNC(=O)[C@@H](CCCCN)NCc1ccccc1)OCCCCCCCCCCCCCC |r| |
|---|
| Structure | 
|
|---|
Search and Browse
