| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
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| Ligand | BDBM50135676 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_161938 |
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| IC50 | 16000±n/a nM |
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| Citation |  Gulledge, BM; Aggen, JB; Chamberlin, AR Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A. Bioorg Med Chem Lett13:2903-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
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| Name: | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B |
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| Synonyms: | Serine-threonine protein phosphatase 2A regulatory subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49694.81 |
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| Organism: | Gallus gallus |
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| Description: | ChEMBL_161937 |
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| Residue: | 426 |
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| Sequence: | DDDVAEADIISTVEFNHCGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHE
PEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDG
RYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRIN
LWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASAL
CDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVE
TYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEA
SRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHHAWHPKENIIAVATTNNLYI
FQDKMN
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| BDBM50135676 |
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| n/a |
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| Name | BDBM50135676 |
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| Synonyms: | (S)-2-[(R)-2-(2-{[(R)-4-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-carboxy-butyryl]-methyl-amino}-acryloylamino)-1-oxo-propylamino]-4-methyl-pentanoic acid | CHEMBL317067 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H59N5O10 |
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| Mol. Mass. | 769.924 |
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| SMILES | CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N[C@H](CCC(=O)N(C)C(=C)C(=O)N[C@H](C)C(=O)N[C@@H](CC(C)C)C(O)=O)C(O)=O |
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| Structure | 
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