| Reaction Details |
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 | Report a problem with these data |
| Target | Protein phosphatase 1A |
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| Ligand | BDBM50135677 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_161761 |
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| IC50 | >100000±n/a nM |
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| Citation |  Gulledge, BM; Aggen, JB; Chamberlin, AR Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A. Bioorg Med Chem Lett13:2903-6 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein phosphatase 1A |
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| Name: | Protein phosphatase 1A |
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| Synonyms: | IA | PP2C-alpha | PPM1A | PPM1A_HUMAN | PPPM1A | Protein phosphatase 1A | Protein phosphatase 2C alpha | Protein phosphatase 2C isoform alpha |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42435.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1438615 |
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| Residue: | 382 |
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| Sequence: | MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD
GHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKH
GADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGG
SVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDG
IWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE
AVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEA
VYNRLNPYKNDDTDSTSTDDMW
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| BDBM50135677 |
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| n/a |
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| Name | BDBM50135677 |
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| Synonyms: | (R)-2-((4E,6E)-(2S,3S,8S,9S)-3-Acetylamino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoylamino)-4-dimethylcarbamoyl-butyric acid | CHEMBL329271 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H43N3O6 |
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| Mol. Mass. | 529.6682 |
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| SMILES | CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@H](NC(C)=O)[C@H](C)C(=O)N[C@H](CCC(=O)N(C)C)C(O)=O |
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| Structure | 
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