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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Protein phosphatase 1A | ||
| Ligand | BDBM50061067 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_161761 | ||
| IC50 | 3±n/a nM | ||
| Citation |  Gulledge, BM; Aggen, JB; Chamberlin, AR Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A. Bioorg Med Chem Lett13:2903-6 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Protein phosphatase 1A | |||
| Name: | Protein phosphatase 1A | ||
| Synonyms: | IA | PP2C-alpha | PPM1A | PPM1A_HUMAN | PPPM1A | Protein phosphatase 1A | Protein phosphatase 2C alpha | Protein phosphatase 2C isoform alpha | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 42435.70 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1438615 | ||
| Residue: | 382 | ||
| Sequence: |
| ||
| BDBM50061067 | |||
| n/a | |||
| Name | BDBM50061067 | ||
| Synonyms: | 15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21heptaaza-cyclopentacosane-11,22-dicarboxylic acid | 15-(3-Guanidino-propyl)-8-isobutyl-18-(6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21heptaaza-cyclopentacosane-11,22-dicarboxylic acid | 8-[3-amino(imino)methylaminopropyl]-15-isobutyl-5-[6-methoxy-3,5-dimethyl-7-phenyl-(1E,3E)-1,3-heptadienyl]-4,11,18,22-tetramethyl-21-methylene-3,7,10,14,17,20,23-heptaoxo-2,6,9,13,16,19,22-heptaazacyclopentacosane-1,12-dicarboxylic acid | CHEMBL444092 | Microcystin-LR | ||
| Type | Small organic molecule | ||
| Emp. Form. | C49H74N10O12 | ||
| Mol. Mass. | 995.1717 | ||
| SMILES | CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]1C)C(O)=O)C(O)=O | ||
| Structure | 
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