| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50135726 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_61005 |
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| Ki | 3±n/a nM |
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| Citation |  Thurkauf, A; Chen, X; Zhang, S; Gao, Y; Kieltyka, A; Wasley, JW; Brodbeck, R; Greenlee, W; Ganguly, A; Zhao, H 1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands. Bioorg Med Chem Lett13:2921-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50135726 |
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| n/a |
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| Name | BDBM50135726 |
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| Synonyms: | 1,6,8-Trimethyl-1,4-dihydro-5,7-dithia-1,2-diaza-as-indacene | CHEMBL100203 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12N2S2 |
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| Mol. Mass. | 236.356 |
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| SMILES | Cc1sc(C)c-2c1SCc1cnn(C)c-21 |
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| Structure | 
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