| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase M |
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| Ligand | BDBM50121929 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_45790 (CHEMBL660086) |
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| IC50 | >50000±n/a nM |
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| Citation |  Barrow, JC; Nantermet, PG; Stauffer, SR; Ngo, PL; Steinbeiser, MA; Mao, SS; Carroll, SS; Bailey, C; Colussi, D; Bosserman, M; Burlein, C; Cook, JJ; Sitko, G; Tiller, PR; Miller-Stein, CM; Rose, M; McMasters, DR; Vacca, JP; Selnick, HG Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem46:5294-7 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase M |
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| Name: | Carboxypeptidase M |
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| Synonyms: | CBPM_HUMAN | CPM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50519.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_45790 |
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| Residue: | 443 |
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| Sequence: | MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL
VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH
IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT
ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD
ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN
KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY
IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP
DHSAATKPSLFLFLVSLLHIFFK
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| BDBM50121929 |
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| n/a |
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| Name | BDBM50121929 |
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| Synonyms: | (phenylmethyl)butanedioic acid | 2-benzylbutanedioic acid | 2-benzylsuccinic acid | CHEMBL151284 | alpha-benzylsuccinic acid | benzylsuccinic acid | beta-carboxybenzenebutanoic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12O4 |
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| Mol. Mass. | 208.2106 |
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| SMILES | OC(=O)CC(Cc1ccccc1)C(O)=O |
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| Structure | 
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