| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix metalloproteinase-26 |
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| Ligand | BDBM50137279 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_104566 |
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| IC50 | 791.0±n/a nM |
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| Citation |  Ma, D; Wu, W; Yang, G; Li, J; Li, J; Ye, Q Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors. Bioorg Med Chem Lett14:47-50 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix metalloproteinase-26 |
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| Name: | Matrix metalloproteinase-26 |
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| Synonyms: | Endometase | MMP-26 | MMP26 | MMP26_HUMAN | Matrilysin-2 | Matrix metalloproteinase 26 | Matrix metalloproteinase-26 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29707.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_806653 |
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| Residue: | 261 |
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| Sequence: | MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQ
FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAV
KDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSG
NPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQL
SADDIQRIQHLYGEKCSSDIP
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| BDBM50137279 |
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| n/a |
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| Name | BDBM50137279 |
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| Synonyms: | 6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide | CHEMBL147489 | N,6-dihydroxy-2-(4-nitrophenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15N3O7S |
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| Mol. Mass. | 393.371 |
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| SMILES | ONC(=O)C1N(CCc2cc(O)ccc12)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O |
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| Structure | 
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