| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 1 |
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| Ligand | BDBM50137352 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105139 |
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| Ki | 33000±n/a nM |
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| Citation |  Hu, X; Zhu, J; Srivathsan, S; Pei, D Peptidyl hydroxamic acids as methionine aminopeptidase inhibitors. Bioorg Med Chem Lett14:77-9 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 1 |
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| Name: | Methionine aminopeptidase 1 |
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| Synonyms: | Aminopeptidase | KIAA0094 | MAP 1 | MAP11_HUMAN | METAP1 | MetAP 1 | Methionine Aminopeptidase Type 1 (MetAP1) | Peptidase M 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 43220.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | MetAP1 with an N-terminal six histidine tag was expressed in baculovirus infected sf9 cells. |
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| Residue: | 386 |
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| Sequence: | MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKA
KREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQ
ALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCY
PSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGE
VDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLF
HTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHT
LLVTDTGCEILTRRLDSARPHFMSQF
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| BDBM50137352 |
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| n/a |
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| Name | BDBM50137352 |
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| Synonyms: | (S)-2-Amino-hexanoic acid hydroxy-[(2-pyridin-2-yl-ethylcarbamoyl)-methyl]-amide | CHEMBL167633 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N4O3 |
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| Mol. Mass. | 308.3761 |
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| SMILES | CCCC[C@H](N)C(=O)N(O)CC(=O)NCCc1ccccn1 |
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| Structure | 
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