| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 2 |
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| Ligand | BDBM50137352 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105144 |
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| Ki | 164000±n/a nM |
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| Citation |  Hu, X; Zhu, J; Srivathsan, S; Pei, D Peptidyl hydroxamic acids as methionine aminopeptidase inhibitors. Bioorg Med Chem Lett14:77-9 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 2 |
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| Name: | Methionine aminopeptidase 2 |
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| Synonyms: | Initiation factor 2-associated 67 kDa glycoprotein | MAP 2 | MAP2_HUMAN | METAP2 | MNPEP | MetAP 2 | Methionine aminopeptidase 2 (MetAP2) | Methionine aminopeptidases (HsMetAP2) | P67EIF2 | Peptidase M 2 | p67 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52884.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50579 |
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| Residue: | 478 |
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| Sequence: | MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
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| BDBM50137352 |
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| n/a |
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| Name | BDBM50137352 |
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| Synonyms: | (S)-2-Amino-hexanoic acid hydroxy-[(2-pyridin-2-yl-ethylcarbamoyl)-methyl]-amide | CHEMBL167633 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N4O3 |
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| Mol. Mass. | 308.3761 |
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| SMILES | CCCC[C@H](N)C(=O)N(O)CC(=O)NCCc1ccccn1 |
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| Structure | 
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