| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50137624 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201426 |
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| Ki | 5484.0±n/a nM |
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| Citation |  Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands. Bioorg Med Chem Lett14:195-202 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50137624 |
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| n/a |
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| Name | BDBM50137624 |
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| Synonyms: | 5-Bromo-N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2-methoxy-benzamide | CHEMBL64261 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25BrN2O4 |
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| Mol. Mass. | 449.338 |
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| SMILES | COc1cc2CCN(CCNC(=O)c3cc(Br)ccc3OC)Cc2cc1OC |
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| Structure | 
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