| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-3 |
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| Ligand | BDBM50138686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_106453 (CHEMBL717837) |
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| Ki | 410±n/a nM |
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| Citation |  Matziari, M; Beau, F; Cuniasse, P; Dive, V; Yiotakis, A Evaluation of P1'-diversified phosphinic peptides leads to the development of highly selective inhibitors of MMP-11. J Med Chem47:325-36 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-3 |
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| Name: | Stromelysin-3 |
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| Synonyms: | MMP11_MOUSE | Matrix metalloproteinase 11 | Mmp11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55452.62 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_106453 |
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| Residue: | 492 |
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| Sequence: | MARAACLLRAISRVLLLPLPLLLLLLLLLPSPLMARARPPESHRHHPVKKGPRLLHAALP
NTLTSVPASHWVPSPAGSSRPLRCGVPDLPDVLNARNRQKRFVLSGGRWEKTDLTYRILR
FPWQLVREQVRQTVAEALQVWSEVTPLTFTEVHEGRADIMIDFARYWHGDNLPFDGPGGI
LAHAFFPKTHREGDVHFDYDETWTIGDNQGTDLLQVAAHEFGHVLGLQHTTAAKALMSPF
YTFRYPLSLSPDDRRGIQHLYGRPQMAPTSPAPTLSSQAGTDTNEIALLEPETPPDVCET
SFDAVSTIRGELFFFKAGFVWRLRSGRLQPGYPALASRHWQGLPSPVDAAFEDAQGQIWF
FQGAQYWVYDGEKPVLGPAPLSKLGLQGSPVHAALVWGPEKNKIYFFRGGDYWRFHPRTQ
RVDNPVPRRSTDWRGVPSEIDAAFQDAEGYAYFLRGHLYWKFDPVKVKVLEGFPRPVGPD
FFDCAEPANTFR
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| BDBM50138686 |
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| n/a |
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| Name | BDBM50138686 |
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| Synonyms: | (1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid | CHEMBL323885 |
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| Type | Small organic molecule |
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| Emp. Form. | C38H38F3N4O7PS |
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| Mol. Mass. | 782.765 |
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| SMILES | NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CSc1ccccc1OC(F)(F)F)CP(O)(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1 |
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| Structure | 
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