| Reaction Details |
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 | Report a problem with these data |
| Target | Dipeptidyl peptidase 1 |
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| Ligand | BDBM50573814 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2120712 (CHEMBL4829859) |
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| IC50 | 408±n/a nM |
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| Citation |  Chen, X; Yan, Y; Zhang, Z; Zhang, F; Liu, M; Du, L; Zhang, H; Shen, X; Zhao, D; Shi, JB; Liu, X Discovery and J Med Chem64:11857-11885 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dipeptidyl peptidase 1 |
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| Name: | Dipeptidyl peptidase 1 |
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| Synonyms: | CATC_HUMAN | CPPI | CTSC | Cathepsin C | Cathepsin J | Dipeptidyl peptidase 1 (DDPI) | Dipeptidyl peptidase 1 (DPPI) | Dipeptidyl peptidase I | Dipeptidyl peptidase I (DPPI) |
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| Type: | Enzyme |
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| Mol. Mass.: | 51857.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P53634 |
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| Residue: | 463 |
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| Sequence: | MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQ
EKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNE
TMTGWVHDVLGRNWACFTGKKVGTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINA
IQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNV
HGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEG
GFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALM
KLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGM
DYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL
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| BDBM50573814 |
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| n/a |
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| Name | BDBM50573814 |
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| Synonyms: | CHEMBL4850341 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18ClF3N6S |
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| Mol. Mass. | 466.91 |
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| SMILES | FC(F)(F)c1cccc(Nc2nc(Nc3ccc(cn3)N3CCSCC3)ncc2Cl)c1 |
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| Structure | 
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