| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 3 |
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| Ligand | BDBM50574230 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2122100 (CHEMBL4831247) |
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| Ki | 79±n/a nM |
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| Citation |  Ericson, MD; Doering, SR; Larson, CM; Freeman, KT; LaVoi, TM; Donow, HM; Santos, RG; Cho, RH; Koerperich, ZM; Giulianotti, MA; Pinilla, C; Houghten, RA; Haskell-Luevano, C Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist. J Med Chem64:14860-14875 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 3 |
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| Name: | Melanocortin receptor 3 |
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| Synonyms: | MC3-R | MC3R_MOUSE | Mc3r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35808.24 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498848 |
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| Residue: | 323 |
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| Sequence: | MNSSCCLSSVSPMLPNLSEHPAAPPASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVI
LAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIAVINSDSLTLEDQFIQHMDNIF
DSMICISLVASICNLLAIAIDRYVTIFYALRYHSIMTVRKALTLIGVIWVCCGICGVMFI
IYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAVLPPAGVVAPQQHSCMKG
AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
FRSLELRNTFKEILCGCNSMNLG
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| BDBM50574230 |
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| n/a |
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| Name | BDBM50574230 |
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| Synonyms: | CHEMBL4851302 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H48IN11O5 |
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| Mol. Mass. | 841.7415 |
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| SMILES | CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| |
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| Structure | 
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