| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase type 2 |
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| Ligand | BDBM26116 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104645 (CHEMBL712891) |
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| IC50 | 21800±n/a nM |
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| Citation |  Buynak, JD; Chen, H; Vogeti, L; Gadhachanda, VR; Buchanan, CA; Palzkill, T; Shaw, RW; Spencer, J; Walsh, TR Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases. Bioorg Med Chem Lett14:1299-304 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase type 2 |
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| Name: | Metallo-beta-lactamase type 2 |
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| Synonyms: | BLAB_BACCE | Beta-lactamase 2 | Metallo-beta-lactamase domain-containing protein 2 | Metallo-beta-lactamase superfamily protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28044.00 |
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| Organism: | Bacillus cereus |
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| Description: | ChEMBL_104097 |
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| Residue: | 256 |
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| Sequence: | MKNTLLKLGVCVSLLGITPFVSTISSVQAERTVEHKVIKNETGTISISQLNKNVWVHTEL
GYFSGEAVPSNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEKKFKKRVTDVIITHAHADR
IGGMKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQSVTNLKFGNMKVETFYPGKGHTE
DNIVVWLPQYQILAGGCLVKSASSKDLGNVADAYVNEWSTSIENVLKRYGNINLVVPGHG
EVGDRGLLLHTLDLLK
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| BDBM26116 |
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| n/a |
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| Name | BDBM26116 |
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| Synonyms: | CHEMBL284104 | Dipicolinate | pyridine carboxylate, 6d | pyridine-2,6-dicarboxylic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C7H5NO4 |
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| Mol. Mass. | 167.1189 |
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| SMILES | OC(=O)c1cccc(n1)C(O)=O |
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| Structure | 
|
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