| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase L1 type 3 |
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| Ligand | BDBM50076678 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104646 (CHEMBL712892) |
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| IC50 | 72300±n/a nM |
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| Citation |  Buynak, JD; Chen, H; Vogeti, L; Gadhachanda, VR; Buchanan, CA; Palzkill, T; Shaw, RW; Spencer, J; Walsh, TR Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases. Bioorg Med Chem Lett14:1299-304 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase L1 type 3 |
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| Name: | Metallo-beta-lactamase L1 type 3 |
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| Synonyms: | BLA1_STEMA | Beta-lactamase L1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30803.13 |
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| Organism: | Stenotrophomonas maltophilia |
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| Description: | ChEMBL_1500319 |
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| Residue: | 290 |
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| Sequence: | MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLT
ALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRR
TGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAG
HTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCD
VLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
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| BDBM50076678 |
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| n/a |
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| Name | BDBM50076678 |
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| Synonyms: | (2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid anion | CHEMBL416561 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H13NO6S |
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| Mol. Mass. | 263.268 |
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| SMILES | CC1(C)[C@@H](N2[C@@H]([C@H](CO)C2=O)S1(=O)=O)C(O)=O |
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| Structure | 
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