| Reaction Details |
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 | Report a problem with these data |
| Target | Peptide deformylase |
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| Ligand | BDBM50089194 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_144950 (CHEMBL755896) |
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| IC50 | <5±n/a nM |
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| Citation |  Molteni, V; He, X; Nabakka, J; Yang, K; Kreusch, A; Gordon, P; Bursulaya, B; Warner, I; Shin, T; Biorac, T; Ryder, NS; Goldberg, R; Doughty, J; He, Y Identification of novel potent bicyclic peptide deformylase inhibitors. Bioorg Med Chem Lett14:1477-81 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptide deformylase |
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| Name: | Peptide deformylase |
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| Synonyms: | DEF_STAAU | PDF | Peptide Deformylase | Polypeptide deformylase | def | def1 | pdf1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 20556.80 |
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| Organism: | Staphylococcus aureus (strain Mu50 / ATCC 700699) |
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| Description: | ChEMBL_459563 |
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| Residue: | 183 |
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| Sequence: | MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVG
LAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAG
LVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKNHPLQPHTDA
VEV
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| BDBM50089194 |
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| n/a |
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| Name | BDBM50089194 |
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| Synonyms: | (R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-pentyl-succinamide | (R)-N4-hydroxy-N1-((S)-1-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)-2-pentylsuccinamide | ACTINONIN | CHEMBL308333 | N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-(R)-pentyl-succinamide | N*4*-Hydroxy-N*1*-[1-(2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-pentyl-succinamide |
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| Type | Small organic molecule |
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| Emp. Form. | C19H35N3O5 |
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| Mol. Mass. | 385.4983 |
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| SMILES | CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO |
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| Structure | 
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