| Reaction Details |
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 | Report a problem with these data |
| Target | Islet amyloid polypeptide |
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| Ligand | BDBM50575507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2125418 (CHEMBL4834763) |
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| IC50 | 3300±n/a nM |
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| Citation |  Hsu, JY; Rao Sathyan, A; Hsu, KC; Chen, LC; Yen, CC; Tseng, HJ; Wu, KC; Liu, HK; Huang, WJ Synthesis of Yakuchinone B-Inspired Inhibitors against Islet Amyloid Polypeptide Aggregation. J Nat Prod84:1096-1103 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Islet amyloid polypeptide |
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| Name: | Islet amyloid polypeptide |
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| Synonyms: | Amylin | DAP | Diabetes-associated peptide | IAPP | IAPP_HUMAN | Insulinoma amyloid peptide | Islet amyloid polypeptide |
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| Type: | PROTEIN |
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| Mol. Mass.: | 9813.88 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_104362 |
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| Residue: | 89 |
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| Sequence: | MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAIL
SSTNVGSNTYGKRNAVEVLKREPLNYLPL
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| BDBM50575507 |
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| n/a |
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| Name | BDBM50575507 |
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| Synonyms: | CHEMBL4861462 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H16O3 |
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| Mol. Mass. | 208.2536 |
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| SMILES | CCCC(=O)CCc1cccc(O)c1O |
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| Structure | 
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