| Reaction Details |
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 | Report a problem with these data |
| Target | Follicle-stimulating hormone receptor |
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| Ligand | BDBM50142680 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_69355 |
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| EC50 | 9.7±n/a nM |
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| Citation |  Guo, T; Adang, AE; Dong, G; Fitzpatrick, D; Geng, P; Ho, KK; Jibilian, CH; Kultgen, SG; Liu, R; McDonald, E; Saionz, KW; Valenzano, KJ; van Straten, NC; Xie, D; Webb, ML Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis. Bioorg Med Chem Lett14:1717-20 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Follicle-stimulating hormone receptor |
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| Name: | Follicle-stimulating hormone receptor |
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| Synonyms: | FSH-R | FSHR | FSHR_HUMAN | Follicle stimulating hormone receptor | Follicle-stimulating hormone receptor | Follitropin receptor | LGR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78273.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1351769 |
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| Residue: | 695 |
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| Sequence: | MALLLVSLLAFLSLGSGCHHRICHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRV
IQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLP
NLQYLLISNTGIKHLPDVHKIHSLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKN
GIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGASGPVILDISRTRIHSLPSYGLEN
LKKLRARSTYNLKKLPTLEKLVALMEASLTYPSHCCAFANWRRQISELHPICNKSILRQE
VDYMTQARGQRSSLAEDNESSYSRGFDMTYTEFDYDLCNEVVDVTCSPKPDAFNPCEDIM
GYNILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIAS
VDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCK
VQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVL
AFVVICGCYIHIYLTVRNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLKVP
LITVSKAKILLVLFHPINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIYRTETSS
TVHNTHPRNGHCSSAPRVTNGSTYILVPLSHLAQN
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| BDBM50142680 |
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| n/a |
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| Name | BDBM50142680 |
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| Synonyms: | CHEMBL46216 | N-[4'-((2S,5S)-1,5-Dimethyl-4-octyl-3,6-dioxo-piperazin-2-ylmethyl)-biphenyl-3-ylmethyl]-N-methoxymethyl-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C32H45N3O4 |
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| Mol. Mass. | 535.7174 |
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| SMILES | CCCCCCCCN1[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)-c2cccc(CN(COC)C(C)=O)c2)C1=O |
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| Structure | 
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