| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thiol:disulfide interchange protein DsbA |
|---|
| Ligand | BDBM50576680 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2127683 (CHEMBL4837028) |
|---|
| Kd | 1137000±n/a nM |
|---|
| Citation |  Duncan, LF; Wang, G; Ilyichova, OV; Dhouib, R; Totsika, M; Scanlon, MJ; Heras, B; Abbott, BM Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg Med Chem45:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thiol:disulfide interchange protein DsbA |
|---|
| Name: | Thiol:disulfide interchange protein DsbA |
|---|
| Synonyms: | DSBA_ECOLI | JW3832 | Thiol:disulfide interchange protein DsbA | dsbA | dsf | dsf | ppfA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 23103.76 |
|---|
| Organism: | Escherichia coli (strain K12) |
|---|
| Description: | ChEMBL_109722 |
|---|
| Residue: | 208 |
|---|
| Sequence: | MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLH
ISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQT
IRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKAAADVQLRGVPAMFVNGKYQL
NPQGMDTSNMDVFVQQYADTVKYLSEKK
|
|
|
|---|
| BDBM50576680 |
|---|
| n/a |
|---|
| Name | BDBM50576680 |
|---|
| Synonyms: | CHEMBL4860222 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H12O3 |
|---|
| Mol. Mass. | 252.2647 |
|---|
| SMILES | OC(=O)Cc1coc2cc(ccc12)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
