| Reaction Details |
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 | Report a problem with these data |
| Target | DNA nucleotidylexotransferase |
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| Ligand | BDBM50143526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210231 |
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| IC50 | 16000±n/a nM |
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| Citation |  Saito, F; Takeuchi, R; Kamino, T; Kuramochi, K; Sugawara, F; Sakaguchi, K; Kobayashi, S Structure-activity relationships of untenone A and its derivatives for inhibition of DNA polymerases. Bioorg Med Chem Lett14:1975-7 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA nucleotidylexotransferase |
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| Name: | DNA nucleotidylexotransferase |
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| Synonyms: | DNA nucleotidylexotransferase | DNTT | TDT | TDT_HUMAN | Terminal addition enzyme | Terminal deoxynucleotidyltransferase | Terminal transferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58545.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_210231 |
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| Residue: | 509 |
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| Sequence: | MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKG
FRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIRAGKPVEMT
GKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCE
FRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAV
LNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLV
SCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQL
LQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSS
WQEGKTWKAIRVDLVLCPYERRAFALLGWTGSRQFERDLRRYATHERKMILDNHALYDKT
KRIFLKAESEEEIFAHLGLDYIEPWERNA
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| BDBM50143526 |
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| n/a |
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| Name | BDBM50143526 |
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| Synonyms: | CHEMBL366792 | Untenone A |
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| Type | Small organic molecule |
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| Emp. Form. | C23H40O4 |
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| Mol. Mass. | 380.5613 |
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| SMILES | CCCCCCCCCCCCCCCC[C@]1(O)C=CC(=O)[C@H]1C(=O)OC |c:18| |
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| Structure | 
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