| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-1 |
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| Ligand | BDBM50141577 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104746 (CHEMBL710746) |
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| Ki | 3.3±n/a nM |
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| Citation |  Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Azasugar-based MMP/ADAM inhibitors as antipsoriatic agents. J Med Chem47:1930-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Stromelysin-1 |
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| Name: | Stromelysin-1 |
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| Synonyms: | MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 53973.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08254 |
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| Residue: | 477 |
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| Sequence: | MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
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| BDBM50141577 |
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| n/a |
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| Name | BDBM50141577 |
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| Synonyms: | (2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide | CHEMBL43087 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20N2O8S |
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| Mol. Mass. | 400.404 |
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| SMILES | CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO |
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| Structure | 
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