| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-arginine deiminase type-3 |
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| Ligand | BDBM50581394 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2151034 (CHEMBL5035496) |
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| IC50 | 26000±n/a nM |
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| Citation |  Yang, C; Dong, ZZ; Zhang, J; Teng, D; Luo, X; Li, D; Zhou, Y Peptidylarginine deiminases 4 as a promising target in drug discovery. Eur J Med Chem226:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-arginine deiminase type-3 |
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| Name: | Protein-arginine deiminase type-3 |
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| Synonyms: | PAD3 | PADI3 | PADI3_HUMAN | PDI3 | Peptidylarginine deiminase III | Protein-arginine deiminase type III |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74727.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1290378 |
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| Residue: | 664 |
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| Sequence: | MSLQRIVRVSLEHPTSAVCVAGVETLVDIYGSVPEGTEMFEVYGTPGVDIYISPNMERGR
ERADTRRWRFDATLEIIVVMNSPSNDLNDSHVQISYHSSHEPLPLAYAVLYLTCVDISLD
CDLNCEGRQDRNFVDKRQWVWGPSGYGGILLVNCDRDDPSCDVQDNCDQHVHCLQDLEDM
SVMVLRTQGPAALFDDHKLVLHTSSYDAKRAQVFHICGPEDVCEAYRHVLGQDKVSYEVP
RLHGDEERFFVEGLSFPDAGFTGLISFHVTLLDDSNEDFSASPIFTDTVVFRVAPWIMTP
STLPPLEVYVCRVRNNTCFVDAVAELARKAGCKLTICPQAENRNDRWIQDEMELGYVQAP
HKTLPVVFDSPRNGELQDFPYKRILGPDFGYVTREPRDRSVSGLDSFGNLEVSPPVVANG
KEYPLGRILIGGNLPGSSGRRVTQVVRDFLHAQKVQPPVELFVDWLAVGHVDEFLSFVPA
PDGKGFRMLLASPGACFKLFQEKQKCGHGRALLFQGVVDDEQVKTISINQVLSNKDLINY
NKFVQSCIDWNREVLKRELGLAECDIIDIPQLFKTERKKATAFFPDLVNMLVLGKHLGIP
KPFGPIINGCCCLEEKVRSLLEPLGLHCTFIDDFTPYHMLHGEVHCGTNVCRKPFSFKWW
NMVP
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| BDBM50581394 |
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| n/a |
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| Name | BDBM50581394 |
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| Synonyms: | CHEMBL5093554 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H29FN6O7 |
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| Mol. Mass. | 448.4466 |
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| SMILES | C[C@@H](O)[C@H](NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)CF)C(N)=O |r| |
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| Structure | 
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