| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50149468 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_41200 (CHEMBL653466) |
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| IC50 | 8±0 nM |
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| Citation |  Tabei, K; Feng, X; Venkatesan, AM; Abe, T; Hideki, U; Mansour, TS; Siegel, MM Mechanism of inactivation of beta-lactamases by novel 6-methylidene penems elucidated using electrospray ionization mass spectrometry. J Med Chem47:3674-88 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | IMI-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32022.80 |
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| Organism: | Enterobacter cloacae |
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| Description: | ChEMBL_522057 |
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| Residue: | 292 |
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| Sequence: | MSLNVKPSRIAILFSSCLVSISFFSQANTKGIDEIKDLETDFNGRIGVYALDTGSGKSFS
YKANERFPLCSSFKGFLAAAVLKGSQDNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSL
GDMAAAALQYSDNGATNIILERYIGGPEGMTKFMRSIGDKDFRLDRWELDLNTAIPGDER
DTSTPAAVAKSLKTLALGNILNEREKETYQTWLKGNTTGAARIRASVPSDWVVGDKTGSC
GAYGTANDYAVVWPKNRAPLIISVYTTKNEKEAKHEDKVIAEASRIAIDNLK
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| BDBM50149468 |
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| n/a |
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| Name | BDBM50149468 |
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| Synonyms: | CHEMBL263746 | Sodium; (R)-6-[1-(5,6-dihydro-8H-imidazo[2,1-c][1,4]oxazin-3-yl)-meth-(Z)-ylidene]-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10N3O4S |
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| Mol. Mass. | 304.302 |
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| SMILES | [O-]C(=O)C1=CS[C@H]2N1C(=O)\C2=C\c1cnc2COCCn12 |t:3| |
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| Structure | 
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