| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 17beta-hydroxysteroid dehydrogenase |
|---|
| Ligand | BDBM50149611 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_306373 (CHEMBL828344) |
|---|
| IC50 | 14000±n/a nM |
|---|
| Citation |  Gobec, S; Sova, M; Kristan, K; Rizner, TL Cinnamic acid esters as potent inhibitors of fungal 17beta-hydroxysteroid dehydrogenase--a model enzyme of the short-chain dehydrogenase/reductase superfamily. Bioorg Med Chem Lett14:3933-6 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 17beta-hydroxysteroid dehydrogenase |
|---|
| Name: | 17beta-hydroxysteroid dehydrogenase |
|---|
| Synonyms: | 17-beta-hydroxysteroid-dehydrogenase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28901.23 |
|---|
| Organism: | Curvularia lunata |
|---|
| Description: | ChEMBL_306373 |
|---|
| Residue: | 270 |
|---|
| Sequence: | MPHVENASETYIPGRLDGKVALVTGSGRGIGAAVAVHLGRLGAKVVVNYANSTKDAEKVV
SEIKALGSDAIAIKADIRQVPEIVKLFDQAVAHFGHLDIAVSNSGVVSFGHLKDVTEEEF
DRVFSLNTRGQFFVAREAYRHLTEGGRIVLTSSNTSKDFSVPKHSLYSGSKGAVDSFVRI
FSKDCGDKKITVNAVAPGGTVTDMFHEVSHHYIPNGTSYTAEQRQQMAAHASPLHRNGWP
QDVANVVGFLVSKEGEWVNGKVLTLDGGAA
|
|
|
|---|
| BDBM50149611 |
|---|
| n/a |
|---|
| Name | BDBM50149611 |
|---|
| Synonyms: | (E)-3-Phenyl-acrylic acid 3,4,5-trimethoxy-benzyl ester | CHEMBL183071 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20O5 |
|---|
| Mol. Mass. | 328.3591 |
|---|
| SMILES | COc1cc(COC(=O)\C=C\c2ccccc2)cc(OC)c1OC |
|---|
| Structure | 
|
|---|
Search and Browse
