Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50150673 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_302905 (CHEMBL830366) | ||
| Ki | 241±n/a nM | ||
| Citation |  Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists. J Med Chem47:3927-30 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | ||
| Type: | Cell-surface receptors | ||
| Mol. Mass.: | 50647.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14416 | ||
| Residue: | 443 | ||
| Sequence: |
| ||
| BDBM50150673 | |||
| n/a | |||
| Name | BDBM50150673 | ||
| Synonyms: | CHEMBL363466 | [(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dimethyl-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H25NO2 | ||
| Mol. Mass. | 311.418 | ||
| SMILES | COc1cccc(OC)c1-c1cccc2C[C@H](CCc12)N(C)C |wD:16.22,(2.58,2.38,;1.26,1.59,;-.09,2.35,;-.11,3.87,;-1.44,4.65,;-2.77,3.85,;-2.75,2.31,;-4.09,1.52,;-4.07,-.02,;-1.42,1.56,;-1.42,.02,;-2.73,-.76,;-2.73,-2.3,;-1.42,-3.07,;-.09,-2.3,;1.25,-3.07,;2.58,-2.32,;2.58,-.78,;1.25,.02,;-.09,-.76,;4.08,-2.72,;4.29,-4.24,;5.24,-1.69,)| | ||
| Structure | 
| ||