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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 1A | ||
| Ligand | BDBM50150686 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_303450 (CHEMBL839710) | ||
| Ki | 174±n/a nM | ||
| Citation |  Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists. J Med Chem47:3927-30 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 1A | |||
| Name: | 5-hydroxytryptamine receptor 1A | ||
| Synonyms: | 5-HT-1A | 5-HT1 | 5-HT1A | 5-Hydroxytryptamine receptor 1A (5-HT1A) | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_RAT | 5ht1a | G-21 | Htr1a | Serotonin 1 (5-HT1) receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1 | Serotonin receptor 1A | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 46445.29 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Binding assays were performed using rat hippocampal membranes. | ||
| Residue: | 422 | ||
| Sequence: |
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| BDBM50150686 | |||
| n/a | |||
| Name | BDBM50150686 | ||
| Synonyms: | CHEMBL182792 | [(R)-8-(2,6-Dimethoxy-phenyl)-chroman-3-yl]-dipropyl-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H31NO3 | ||
| Mol. Mass. | 369.4971 | ||
| SMILES | CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1c(OC)cccc1OC |wD:7.6,(1.92,-6.31,;1.94,-4.77,;3.27,-4,;3.27,-2.46,;4.6,-1.69,;5.93,-2.46,;7.28,-1.69,;1.94,-1.68,;1.94,-.12,;.58,.65,;-.75,-.12,;-.75,-1.68,;.58,-2.46,;-2.08,-2.43,;-3.41,-1.66,;-3.41,-.12,;-2.08,.65,;-2.09,2.19,;-.76,2.96,;.58,2.19,;1.91,2.96,;-.76,4.5,;-2.1,5.27,;-3.45,4.47,;-3.42,2.94,;-4.75,2.16,;-6.09,2.92,)| | ||
| Structure | 
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