| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 3 |
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| Ligand | BDBM50151502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302996 (CHEMBL830235) |
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| Ki | 15000±n/a nM |
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| Citation |  Mutulis, F; Yahorava, S; Mutule, I; Yahorau, A; Liepinsh, E; Kopantshuk, S; Veiksina, S; Tars, K; Belyakov, S; Mishnev, A; Rinken, A; Wikberg, JE New substituted piperazines as ligands for melanocortin receptors. Correlation to the X-ray structure of"THIQ". J Med Chem47:4613-26 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 3 |
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| Name: | Melanocortin receptor 3 |
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| Synonyms: | MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36044.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41968 |
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| Residue: | 323 |
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| Sequence: | MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI
LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF
DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI
VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG
AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
FRSLELRNTFREILCGCNGMNLG
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| BDBM50151502 |
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| n/a |
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| Name | BDBM50151502 |
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| Synonyms: | 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-phenyl-piperazin-1-yl)-ethyl]-amide | CHEMBL185195 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31ClN4O2 |
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| Mol. Mass. | 503.035 |
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| SMILES | Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCN(CC2)c2ccccc2)cc1 |
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| Structure | 
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