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TargetMelanocyte-stimulating hormone receptor
LigandBDBM50152246
Substrate/Competitorn/a
Meas. Tech.ChEMBL_310167 (CHEMBL824823)
EC50 0.009±n/a nM
Citation Koikov, LN; Ebetino, FH; Hayes, JC; Cross-Doersen, D; Knittel, JJ End-capping of the modified melanocortin tetrapeptide (p-Cl)Phe-D-Phe-Arg-Trp-NH2 as a route to hMC4R agonists. Bioorg Med Chem Lett14:4839-42 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melanocyte-stimulating hormone receptor
Name:Melanocyte-stimulating hormone receptor
Synonyms:MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:Enzyme
Mol. Mass.:34717.23
Organism:Homo sapiens (Human)
Description:Q01726
Residue:317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV
ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI
DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI
AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA
VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF
HSQELRRTLKEVLTCSW
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BDBM50152246
n/a
NameBDBM50152246
Synonyms:(S)-5-Guanidino-2-((S)-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)-2-(4-phenyl-butyrylamino)-propionylamino]-3-phenyl-propionylamino}-3-phenyl-propionylamino)-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide | CHEMBL384720
TypeSmall organic molecule
Emp. Form.C51H60N12O6
Mol. Mass.937.0989
SMILESNC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Structure
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