| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50152297 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303584 (CHEMBL828125) |
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| Ki | 3±n/a nM |
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| Citation |  Egle, I; Barriault, N; Bordeleau, M; Drage, J; Dube, L; Peragine, J; Mazzocco, L; Arora, J; Jarvie, K; Tehim, A N-(1-Benzylpyrrolidin-3-yl)arylbenzamides as potent and selective human dopamine D4 antagonists. Bioorg Med Chem Lett14:4847-50 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50152297 |
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| n/a |
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| Name | BDBM50152297 |
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| Synonyms: | CHEMBL187236 | N-(1-Benzyl-pyrrolidin-3-yl)-4-thiophen-2-yl-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N2OS |
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| Mol. Mass. | 362.488 |
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| SMILES | O=C(NC1CCN(Cc2ccccc2)C1)c1ccc(cc1)-c1cccs1 |
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| Structure | 
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