| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP3 subtype |
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| Ligand | BDBM50152512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303669 (CHEMBL830430) |
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| Ki | 1700±n/a nM |
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| Citation |  Torisu, K; Kobayashi, K; Iwahashi, M; Nakai, Y; Onoda, T; Nagase, T; Sugimoto, I; Okada, Y; Matsumoto, R; Nanbu, F; Ohuchida, S; Nakai, H; Toda, M Discovery of orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett14:4891-5 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP3 subtype |
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| Name: | Prostaglandin E2 receptor EP3 subtype |
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| Synonyms: | PE2R3_MOUSE | PGE receptor, EP3 isoform alpha | Prostaglandin E2 receptor EP3 isoform alpha | Prostaglandin E3 | Prostanoid EP3 receptor | Ptger3 | Ptgerep3 |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 40092.50 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 365 |
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| Sequence: | MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESK
RKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLS
SLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWP
GTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKA
AVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKE
CNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWS
DQLER
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| BDBM50152512 |
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| n/a |
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| Name | BDBM50152512 |
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| Synonyms: | CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C28H25FN2O5 |
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| Mol. Mass. | 488.5069 |
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| SMILES | CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2cc(F)ccc12 |
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| Structure | 
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