Reaction Details |
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Target | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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Ligand | BDBM50583528 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2157652 (CHEMBL5042312) |
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Ki | >1000±n/a nM |
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Citation | Guo, M; He, S; Cheng, J; Li, Y; Dong, G; Sheng, C Hydrophobic Tagging-Induced Degradation of PDE? in Colon Cancer Cells. ACS Med Chem Lett13:298-303 (2022) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
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Name: | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
Synonyms: | 3',5'-cyclic phosphodiesterase | GMP-PDE delta | PDE6D | PDE6D_HUMAN | PDED | Protein p17 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
Type: | PROTEIN |
Mol. Mass.: | 17418.30 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_105761 |
Residue: | 150 |
Sequence: | MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS
RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA
SVLTGNVIIETKFFDDDLLVSTSRVRLFYV
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BDBM50583528 |
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n/a |
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Name | BDBM50583528 |
Synonyms: | CHEMBL5092958 |
Type | Small organic molecule |
Emp. Form. | C48H65N7O4 |
Mol. Mass. | 804.0742 |
SMILES | Cc1n(nc2c1c(C)nn(CCCC(=O)NCCc1ccc(NC(=O)CCCCCCCCCC(=O)NCC34CC5CC(CC(C5)C3)C4)cc1)c2=O)-c1ccc(C)cc1 |TLB:41:42:39.40.45:46,THB:41:40:46:47.42.43,43:42:39:45.44.46,43:44:39:47.41.42| |
Structure |
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