| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Ligand | BDBM50583532 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2157652 (CHEMBL5042312) |
|---|
| Ki | 41±n/a nM |
|---|
| Citation |  Guo, M; He, S; Cheng, J; Li, Y; Dong, G; Sheng, C Hydrophobic Tagging-Induced Degradation of PDE? in Colon Cancer Cells. ACS Med Chem Lett13:298-303 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Name: | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Synonyms: | 3',5'-cyclic phosphodiesterase | GMP-PDE delta | PDE6D | PDE6D_HUMAN | PDED | Protein p17 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 17418.30 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_105761 |
|---|
| Residue: | 150 |
|---|
| Sequence: | MSAKDERAREILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVS
RELNFSSTEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPA
SVLTGNVIIETKFFDDDLLVSTSRVRLFYV
|
|
|
|---|
| BDBM50583532 |
|---|
| n/a |
|---|
| Name | BDBM50583532 |
|---|
| Synonyms: | CHEMBL5079726 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H44N6O3 |
|---|
| Mol. Mass. | 572.7409 |
|---|
| SMILES | Cc1n(nc2c1c(C)nn(CCCC(=O)NCCCC(=O)NCC13CC4CC(CC(C4)C1)C3)c2=O)-c1ccc(C)cc1 |TLB:26:27:24.25.30:31,THB:26:25:31:32.27.28,28:27:24:30.29.31,28:29:24:32.26.27| |
|---|
| Structure | 
|
|---|
Search and Browse
