| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
|---|
| Ligand | BDBM50077217 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2158238 (CHEMBL5042988) |
|---|
| IC50 | 2.0±n/a nM |
|---|
| Citation |  Szeleczky, Z; Szakács, Z; Bozó, É; Baska, F; Vukics, K; Lévai, S; Temesvári, K; Vass, E; Béni, Z; Krámos, B; Magdó, I; Szántay, C; Kóti, J; Domány-Kovács, K; Greiner, I; Bata, I Synthesis and Characterization of New V J Med Chem64:10445-10468 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V1a receptor |
|---|
| Name: | Vasopressin V1a receptor |
|---|
| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
|---|
| Type: | Receptor |
|---|
| Mol. Mass.: | 46820.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P37288 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
|
|
|
|---|
| BDBM50077217 |
|---|
| n/a |
|---|
| Name | BDBM50077217 |
|---|
| Synonyms: | CHEMBL3416885 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H28ClN3O2 |
|---|
| Mol. Mass. | 437.962 |
|---|
| SMILES | CN(C)CCn1cc(C(=O)N2CCC3(CC2)OCc2ccccc32)c2ccc(Cl)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
